Sefer Ha-Peulot is one of the most revealing — and most neglected — texts in the Lurianic corpus. Where Vital's great theological works present a systematic architecture of divine worlds, this notebook shows the same man from another angle: restless, eclectic, and hungry for practical results. Medicine, amulets, dream induction, love magic, and alchemy coexist in its pages, drawing on Jewish tradition while incorporating material traceable to Latin alchemical sources — evidence of the cross-confessional knowledge networks connecting Safed to Ottoman Istanbul and Renaissance Italy. This first reliable edition reconstructs the text from several manuscripts and identifies its sources across Hebrew, Latin, Italian, and Spanish traditions. An essential document for historians of Jewish mysticism, early modern science, and the transmission of knowledge across religious boundaries.